{"id":367089,"date":"2026-10-29T06:30:00","date_gmt":"2026-10-29T05:30:00","guid":{"rendered":"https:\/\/legrandcontinent.eu\/fr\/?p=367089"},"modified":"2026-10-28T23:16:49","modified_gmt":"2026-10-28T22:16:49","slug":"lhubris-de-citrini-quand-lia-devient-la-nouvelle-cocaine-des-traders","status":"publish","type":"post","link":"https:\/\/legrandcontinent.eu\/fr\/2026\/10\/29\/lhubris-de-citrini-quand-lia-devient-la-nouvelle-cocaine-des-traders\/","title":{"rendered":"L\u2019hubris de Citrini&#160;: quand l\u2019IA devient la nouvelle coca\u00efne des traders"},"content":{"rendered":"\n<p>Mardi 20 octobre, les traders de la firme am\u00e9ricaine de recherche en investissement Citrini ont publi\u00e9 un article dans lequel ils annoncent avoir con\u00e7u, avec un mod\u00e8le de recherche interne d\u2019Anthropic, des prot\u00e9ines capables de se lier aux neurotoxines du venin de scorpion&nbsp;<span class='whitespace-nowrap'><span id='easy-footnote-1-367089' class='easy-footnote-margin-adjust'><\/span><span class='easy-footnote note-digits-1'><a href='https:\/\/legrandcontinent.eu\/fr\/2026\/10\/29\/lhubris-de-citrini-quand-lia-devient-la-nouvelle-cocaine-des-traders\/#easy-footnote-bottom-1-367089' title='\u00a0&lt;a href=&quot;https:\/\/www.citriniresearch.com\/p\/citrini-therapeutics&quot;&gt;Citrini Therapeutics&lt;\/a&gt;, Citrini Research, 20 octobre 2026.'><sup>1<\/sup><\/a><\/span><\/span>.<\/p>\n\n\n\n<p>Ces derniers pr\u00e9cisent ne rien conna\u00eetre \u00e0 la biologie \u2013 et aux sciences de mani\u00e8re g\u00e9n\u00e9rale.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Le m\u00eame jour, Anthropic a publi\u00e9 un rapport technique sur cette exp\u00e9rience, men\u00e9e sur son r\u00e9seau et ses machines. Les garde-fous de bios\u00e9curit\u00e9 du Claude commercialis\u00e9 avaient en effet bloqu\u00e9 les traders d\u00e8s leur premi\u00e8re requ\u00eate.<\/li>\n\n\n\n<li>En 64 heures, celui-ci a g\u00e9n\u00e9r\u00e9 plus de 318 000 designs de prot\u00e9ines et en a retenu 180. Avec 31 ajouts ult\u00e9rieurs, 211 ont \u00e9t\u00e9 test\u00e9s en laboratoire et 17 ont rempli les crit\u00e8res de liaison fix\u00e9s.<\/li>\n\n\n\n<li>Le projet, qui a dur\u00e9 trois mois, a co\u00fbt\u00e9 \u00e0 Citrini environ 200 000 dollars, dont 50 000 en puissance de calcul.<\/li>\n<\/ul>\n\n\n\n<p>L\u2019\u00e9quipe de Citrini revendique avoir fait, en trois mois et \u00e0 cinq, ce que le d\u00e9veloppement classique d\u2019un antivenin demande d\u2019ordinaire \u00e0 des laboratoires sp\u00e9cialis\u00e9s. Les traders reconnaissent n\u2019avoir mis aucun m\u00e9dicament sur le march\u00e9 et n\u2019avoir rien publi\u00e9 de scientifiquement significatif, mais estiment toutefois que \u00ab&#160;la fronti\u00e8re a boug\u00e9&#160;\u00bb.<\/p>\n\n\n\n\n\n<figure class=\"wp-block-image wp-block-image-medium\"\n    data-shadow=\"false\"\n    data-use-original-file=\"false\">\n    <a\n        data-pswp-src=\"https:\/\/legrandcontinent.eu\/fr\/wp-content\/uploads\/sites\/2\/2026\/10\/Hubris-Citrini.png\"\n        class=\"inline-block gallery-item no-underline \"\n        data-pswp-width=\"1456\"\n        data-pswp-height=\"1814\">\n                                        <picture>\r\n                    <source\r\n                srcset=\"https:\/\/legrandcontinent.eu\/fr\/wp-content\/uploads\/sites\/2\/2026\/10\/Hubris-Citrini-330x411.png\"\r\n                media=\"(max-width:  374px)\" \/>\r\n                    <source\r\n                srcset=\"https:\/\/legrandcontinent.eu\/fr\/wp-content\/uploads\/sites\/2\/2026\/10\/Hubris-Citrini-690x860.png\"\r\n                media=\"(max-width:  989px)\" \/>\r\n                    <source\r\n                srcset=\"https:\/\/legrandcontinent.eu\/fr\/wp-content\/uploads\/sites\/2\/2026\/10\/Hubris-Citrini-990x1233.png\"\r\n                media=\"(max-width: 1319px)\" \/>\r\n                    <source\r\n                srcset=\"https:\/\/legrandcontinent.eu\/fr\/wp-content\/uploads\/sites\/2\/2026\/10\/Hubris-Citrini-690x860.png\"\r\n                media=\"(max-width: 1599px)\" \/>\r\n                    <source\r\n                srcset=\"https:\/\/legrandcontinent.eu\/fr\/wp-content\/uploads\/sites\/2\/2026\/10\/Hubris-Citrini-990x1233.png\"\r\n                media=\"(min-width: 1600px)\" \/>\r\n                <img decoding=\"async\" src=\"https:\/\/legrandcontinent.eu\/fr\/wp-content\/uploads\/sites\/2\/2026\/10\/Hubris-Citrini-125x156.png\" \/>\r\n        <\/picture>\r\n                            \n                    <figcaption class=\"pswp-caption-content \">Le plan de bataille des traders de Citrini. Sur la frise du d\u00e9veloppement d\u2019un m\u00e9dicament, qui court de l\u2019identification de la maladie jusqu\u2019au remboursement par les assurances, l\u2019exp\u00e9rience ne couvre que les deux premi\u00e8res cases. \u00a9 Citrini Research<\/figcaption>\n            <\/a>\n<\/figure>\n\n\n<p>Comment expliquer ce prodige&#160;?&nbsp;<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Comme pour Anthropic, qui avait <a href=\"https:\/\/legrandcontinent.eu\/fr\/2026\/09\/24\/que-revele-la-decouverte-par-anthropic-dune-nouvelle-enzyme\/\">annonc\u00e9<\/a> fin septembre la d\u00e9couverte par Claude d\u2019un syst\u00e8me enzymatique in\u00e9dit \u00e0 r\u00e9p\u00e9titions de type CRISPR, l\u2019objectif principal de Citrini semble \u00eatre de faire de la publicit\u00e9.<\/li>\n\n\n\n<li>\u00c0 la fin de l\u2019article, en acc\u00e8s ouvert, ils pr\u00e9sentent un autre article, payant, o\u00f9 ils expliquent tout ce que cette \u00ab&#160;exp\u00e9rience&#160;\u00bb leur a appris et prodiguent les conseils en investissement que cela leur inspire.<\/li>\n<\/ul>\n\n\n\n<p>La phrase la plus r\u00e9v\u00e9latrice de cette exp\u00e9rience est celle o\u00f9 les traders se f\u00e9licitent que \u00ab&#160;leur invention digitale va d\u00e9sormais cr\u00e9er du travail pour des scientifiques humains&#160;\u00bb. On ne peut pas exclure que quelque chose \u00e9merge de ces travaux, puisque certaines d\u00e9couvertes majeures ont \u00e9t\u00e9 faites de fa\u00e7on iconoclaste.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Il est cependant tr\u00e8s probable que les \u00ab&#160;scientifiques&#160;\u00bb pour lesquels ces traders ont \u00ab&#160;cr\u00e9\u00e9 du travail&#160;\u00bb eussent fait un bien meilleur usage des 200 000 dollars que Citrini a engag\u00e9s dans cette \u00ab&#160;exp\u00e9rience&#160;\u00bb.<\/li>\n\n\n\n<li>Et \u00e9tant donn\u00e9 l\u2019\u00e9tat du financement de la recherche, si Citrini y met le prix, il est probable que des chercheurs comp\u00e9tents finissent par travailler sur ses r\u00e9sultats.<\/li>\n<\/ul>\n\n\n\n<p>L\u2019IA aspire d\u00e9j\u00e0 une part d\u00e9mesur\u00e9e du capital disponible, au d\u00e9triment d\u2019autres projets potentiellement aussi prometteurs. Ce type \u00ab&#160;d\u2019exp\u00e9riences&#160;\u00bb fait peser le m\u00eame risque sur l\u2019allocation des ressources scientifiques.<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Pendant la pand\u00e9mie de Covid-19, la controverse sur l\u2019hydroxychloroquine a ainsi pouss\u00e9 soignants et chercheurs \u00e0 multiplier les protocoles d\u2019essais.<\/li>\n\n\n\n<li>Il est assez rapidement apparu que la mol\u00e9cule \u00e9tait probablement efficace in vitro mais inefficace in vivo.<\/li>\n\n\n\n<li>La pression populaire a pourtant conduit \u00e0 continuer \u00e0 la tester, au d\u00e9triment d\u2019autres pistes de traitement.<\/li>\n<\/ul>\n\n\n\n<p>Que se passerait-il si demain ce n\u2019\u00e9taient plus des traders mais Barron Trump, le fils du pr\u00e9sident am\u00e9ricain, qui annonce la d\u00e9couverte \u00ab&#160;d\u2019une nouvelle mol\u00e9cule r\u00e9volutionnaire&#160;\u00bb gr\u00e2ce \u00e0 l\u2019IA&#160;? Trump pourrait alors contraindre des chercheurs financ\u00e9s par le gouvernement f\u00e9d\u00e9ral \u00e0 consacrer leur temps et leurs ressources \u00e0 \u00ab&#160;investiguer&#160;\u00bb cette mol\u00e9cule \u2013 au d\u00e9triment d\u2019autres travaux bien plus pertinents.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>50 000 dollars de puissance de calcul suffisent-ils pour cr\u00e9er un antivenin&#160;?<\/p>\n","protected":false},"author":2622,"featured_media":367091,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"templates\/post-briefings.php","format":"standard","meta":{"_acf_changed":false,"_trash_the_other_posts":false,"_yoast_wpseo_estimated-reading-time-minutes":3,"_lgc_tts_voice":"","_lgc_tts_publish":false,"_lgc_tts_history_item_id":"","_lgc_tts_generated_at":"","_lgc_tts_status":"","_lgc_tts_error":"","footnotes":""},"categories":[2040],"tags":[],"staff":[2209],"editorial_format":[4942],"serie":[],"audience":[],"geo":[525],"class_list":["post-367089","post","type-post","status-publish","format-standard","hentry","category-science","staff-xavier-olessa-daragon","editorial_format-actu-breves","geo-ameriques"],"acf":{"open_in_webview":false,"accent":"default","_thumbnail_id":367091,"excerpt":"50 000 dollars de puissance de calcul suffisent-ils pour cr\u00e9er un antivenin ?","display_date":"","new_abstract":true},"yoast_head":"<!-- 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